Insulin Versus Hyaluronic Acid in Management of Periodontal Defects

Phase 3

Recruiting

• Conditions: Periodontal Diseases; Periodontal Pocket
• Interventions: Drug: Insulin; Drug: Hyaluronic acid

• Registration Number: NCT05746676
• Lead Sponsor: October University for Modern Sciences and Arts

Brief Summary

in this study, insulin and hyaluronic acid will be used after open flap debridement in treatment of periodontal defects. outcome will be evaluated clinically and radiographically

Detailed Description

n this study, insulin versus hyaluronic acid will be used after open flap debridement in treatment of periodontal defects. outcome will be evaluated clinically and radiographically after a follow up period

Study Timeline

• Study Start: 2023-01-12
• Status Verified: 2023-02
• Study First Submitted: 2023-02-13
• Study First Submitted QC: 2023-02-25
• Last Update Submitted: 2023-02-25
• Study First Posted: 2023-02-28
• Last Update Posted: 2023-02-28
• Primary Completion: 2023-08
• Study Completion: 2023-10

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• patients diagnosed with periodontitis

Exclusion Criteria

• patients with systemic illness that contraindicate periodontal surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
group 1	Insulin	-
group 2	Hyaluronic acid	-

Primary Outcome Measures

Name	Time	Method
clinical evaluation	6 months	periodontal pocket depth
radiographic evaluation	6 months	bone gain assessed by cone beam computed tomography

Trial Locations

Locations (1)

Al-Azhar University, Faculty of Dentistry; 🇪🇬 Cairo, Egypt