The BRAvAdO Registry

• Conditions: Oncology; ACS - Acute Coronary Syndrome

• Registration Number: NCT04222608
• Lead Sponsor: University of Sao Paulo General Hospital

Brief Summary

The BRAVADO Registry pretends to identify stratification, diagnosis, total atherosclerotic burden and treatment approaches in oncologic patients with Acute Coronary Syndrome (ACS) and identify strategies to improve health care quality

Detailed Description

Not available

Study Timeline

• Study Start: 2016-09-01
• Status Verified: 2019-11
• Study First Submitted: 2019-11-13
• Study First Submitted QC: 2020-01-06
• Last Update Submitted: 2020-01-06
• Study First Posted: 2020-01-10
• Last Update Posted: 2020-01-10
• Primary Completion: 2021-09-01
• Study Completion: 2021-09-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

• Definitive cancer diagnosis - biopsy
• Acute Coronary Syndrome - requiring urgent invasive risk stratification

Exclusion Criteria

• KPS < 60 , ECOG >/ 3
• Life expectancy less 24hs
• End of Life Care
• Lack of consistent record data

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total Atherosclerotic burden and lesion complexity on angiography	30 days	The number and location of coronary lesions with obstructions greater than 50% were recorded. Each lesion was classified based on Ambrose's, Goldstein complexity, Leaman and SYNTAX scores.
Major adverse cardiovascular events	30 days	Composite endpoint of All-cause Death, Myocardial Infarction, Stroke and Myocardial Revascularization
Incidence of Major Bleeding	30 days	Requiring a transfusion of ≥2 U PRBCs Resulting in a decrease in hematocrit of ≥10% Occurring intracerebrally Resulting in stroke or death

Trial Locations

Locations (1)

Carlos M Campos; 🇧🇷 São Paulo, Brazil