Effect of Reducing Medication Regimen Complexity on Glycemic Control in Patients With Diabetes.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- Change in Hemoglobin A1c
研究概览
简要总结
Polypharmacy is an alarming health issue that is defined as prescription of multiple medications, of which some are redundant or unnecessary. Due to comorbidities, diabetic patients are often prescribed multiple medications. Over prescribing occurs either due to, prescribing medications that are not indicated, continuation of certain medications beyond the time of indication, or prescribing more than one medication with the same effect. Improving glycaemic control is the cornerstone for the prevention and treatment of the diabetic complications.
详细描述
Hypothesis In addition to the side effects and cost of the unnecessary medications, the investigators hypothesis is that poly-pharmacy will adversely affect patients' compliance with the necessary medications.The investigators propose that elimination of unnecessary medications might improve patients' compliance and consequently improve glycemic control diabetic patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All diabetic patients who are eligible by fulfilling all of the following criteria:
- •HGBA1c ≥7 mg/dl.
- •Poly-pharmacy: defined as the use of five or more medications.
- •Non- compliance: patients were surveyed with both direct and indirect methods to identify non adherence.
排除标准
- •Exclusion after recruitment Any patient whose diabetic medications regimen changed after recruitment due to hospitalisation, illness, stress or patients preference, will be excluded.
研究组 & 干预措施
Diabetic patients with non-adherence and poly-pharmacy
Medications review. Elimination of all unnecessary prescription to cut down the number of medications to the least possible number.
干预措施: Medications review (Other)
结局指标
主要结局
Change in Hemoglobin A1c
时间窗: 3 months
measurement of hemoglobin A1c to determine glycemic control.
次要结局
未报告次要终点
研究者
Tarek Samy Abdelziz
Senior lecturer
Kasr El Aini Hospital