NCT06125899尚未招募不适用
Intervention for Depression in Underserved Geriatric Populations
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 110
- 主要终点
- Depression remission
研究概览
简要总结
The aim of this hybrid (Effectiveness-Implementation) cluster randomised controlled clinical trial is to test the feasibility of implementing an age-appropriate electronic version of the WHO Mental Health Gap Action Programme Intervention Guide (emhGAP-Age) in routine home-based care of older Nigerians with depression. The main questions it aims to answer are:
- Whether the emhGAP-Age demonstrate sufficient signals of effectiveness in the identification and home management of late life depression to permit for further exploration in a fully powered clinical trial?
- What are the logistical, programmatic, and operational requirements for a home-delivered emhGAP-Age in a sample of older people with depression in Nigeria? Consenting older participants with depression in the intervention arm will receive treatment based on emhGAP-Age which consists of;
- Adapted electronic generic version of the WHO Mental Health Gap Action Programme Intervention Guide (emhGAP-IG)
- Adapted Problem-Solving Therapy (PST-PC)
- Support/supervision of providers
- Links to social support resources. Researchers will compare with treatment based on the basic specification in the generic emhGAP-IG (consisting of basic psychoeducation and stress reduction) for effects on depression remission.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 60 years,
- •PHQ-9 score of ≥11 during routine consultation
排除标准
- •Severe co-morbidity requiring urgent attention.
- •Severe cognitive impairment/dementia (Community Screening Instruments for Dementia score≤ 20) .
- •Active suicidal intention.
- •Evidence of bipolar/psychosis/severe substance use disorders.
- •Planning to move out of the study catchment area within 6 months.
- •Refusing/lacking capacity to consent/accent
结局指标
主要结局
Depression remission
时间窗: At six months post trial entry
Patient Health Questionnaire (PHQ-9) score \< 6
次要结局
未报告次要终点
研究者
Akin Ojagbemi
Senior Lecturer
University of Ibadan
相似试验
已完成
不适用
Enhancing the Clinical Effectiveness of Depression Screening Using Patient-targeted Feedback in General PracticesDepressionNCT03988985Universitätsklinikum Hamburg-Eppendorf1,030
已完成
2 期
Dose-finding Study With Lu AA24530 in Major Depressive DisorderMajor Depressive DisorderNCT00599911H. Lundbeck A/S652
Enrolling By Invitation
不适用
Adolescent Depression Screening and Treatment in Mozambican Primary CareAdolescent BehaviorDepressionNCT05476237Columbia University114
已完成
2 期
Effectiveness of Ascorbic Acid and Tocopherol for Depression in Elderly.DepressionNCT02793648Yolanda de Diego Otero50
已完成
不适用
Depression Intervention Among Gay and Bisexual Men Receiving Treatment for Methamphetamine UseHIV/AIDSMethamphetamine AbuseDepressionNCT03864653Friends Research Institute, Inc.39
