Skip to main content
Clinical Trials/NCT06125899
NCT06125899
Not yet recruiting
Not Applicable

Intervention for Depression in Underserved Geriatric Populations

University of Ibadan0 sites110 target enrollmentFebruary 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Depression in Old Age
Sponsor
University of Ibadan
Enrollment
110
Primary Endpoint
Depression remission
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

The aim of this hybrid (Effectiveness-Implementation) cluster randomised controlled clinical trial is to test the feasibility of implementing an age-appropriate electronic version of the WHO Mental Health Gap Action Programme Intervention Guide (emhGAP-Age) in routine home-based care of older Nigerians with depression. The main questions it aims to answer are:

  1. Whether the emhGAP-Age demonstrate sufficient signals of effectiveness in the identification and home management of late life depression to permit for further exploration in a fully powered clinical trial?

  2. What are the logistical, programmatic, and operational requirements for a home-delivered emhGAP-Age in a sample of older people with depression in Nigeria? Consenting older participants with depression in the intervention arm will receive treatment based on emhGAP-Age which consists of;

    • Adapted electronic generic version of the WHO Mental Health Gap Action Programme Intervention Guide (emhGAP-IG)
    • Adapted Problem-Solving Therapy (PST-PC)
    • Support/supervision of providers
    • Links to social support resources. Researchers will compare with treatment based on the basic specification in the generic emhGAP-IG (consisting of basic psychoeducation and stress reduction) for effects on depression remission.
Registry
clinicaltrials.gov
Start Date
February 2024
End Date
July 2025
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Akin Ojagbemi

Senior Lecturer

University of Ibadan

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 60 years,
  • PHQ-9 score of ≥11 during routine consultation

Exclusion Criteria

  • Severe co-morbidity requiring urgent attention.
  • Severe cognitive impairment/dementia (Community Screening Instruments for Dementia score≤ 20) .
  • Active suicidal intention.
  • Evidence of bipolar/psychosis/severe substance use disorders.
  • Planning to move out of the study catchment area within 6 months.
  • Refusing/lacking capacity to consent/accent

Outcomes

Primary Outcomes

Depression remission

Time Frame: At six months post trial entry

Patient Health Questionnaire (PHQ-9) score \< 6

Similar Trials