Regulation of muscle oxidative phenotype by hypoxia in Chronic Obstructive Pulmonary Disease and Chronic Heart Failure - Regulation of muscle oxidative phenotype

niversiteit Maastricht0 个研究点目标入组 90 人开始时间: 待定最近更新: 2024年5月13日

适应症

试验速览

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•COPD patients: inclusion criterion for COPD patients is COPD according to GOLD criteria.
•Heart failure patients: inclusion criterion for CHF patients is diagnosis heart failure with an ejection fraction < 40% determined by echocardiography

•COPD patients: exclusion criteria for COPD patients are malignancy, cardiac failure, distal arteriopathy, recent surgery, severe endocrine, hepatic or renal disorders, oxygen therapy and recent participation in a revalidation program (previous 6 months).
•CHF patients: exclusion criteria for CHF patients are unstable disease, unstable angina pectoris, correctable cause of heart failure or valvular heart disease, restrictive or hypertrophic cardiomyopathy, malignancy, pulmonary disease (including primary pulmonary hypertension and COPD), distal arteriopathy, recent surgery, severe endocrine, hepatic or renal disorders and recent participation in a revalidation program (previous 6 months).
•Patients with artificial valves, known left ventricular thrombi and mitral stenosis will also be excluded.

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