The effect of the laser photocoagulation method in treatment of diabetic macular edema

Not Applicable

• Conditions: diabetic macular edema.; Diabetic retinopathy (E10-E14 with common fourth character .3+)

• Registration Number: IRCT2015122721890N2
• Lead Sponsor: Vice Chancellor for Research, Isfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

at least best corrected vision 20/200 or 1.00 LogMAR; the best corrected vision less than 20/25 or 0.10 LogMAR; diabetic macular edema with at least central macular thickness of 300 microns
Exclusion criteria: monocular patients; diabetic macular edema with central macular thickness more than 450 microns; pregnant patients; uncontrolled diabetes mellitus defined with fasting blood glucose (FBS) more than 300 mg/dl and or Hb A1c?10 mg/dl; uncontrolled hypertension defined with systolic blood pressure SBP more than 160 mmHg and or diastolic blood pressure (DBP) more than 110 mmHg; any history of intra orbital surgery except uncomplicated cataract surgery with phacoemulsification method; any history of previously intra ocular injection; any history of previously conventional laser photocoagulation of retina or subthreshold diode micropulse laser; previously history of glaucoma or ocular hypertension; macular diseases like vitreo macular traction(VMT), Epi retinal Membrane (ERM), Age related macular degeneration (AMD), proliferative diabetic retinopathy (PDR); extensive non capillary perfusion in fundus angiography of macula; pregnancy during the study; any visible scar in ophthalmic examination or fundus angiography during the study in group that treated with subthreshold diode micropulse laser; not follow up of patients; no acceptance to perform study.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Best corrected visual acuity. Timepoint: 0, ,2, 4 Months. Method of measurement: With Snellen chart and then converted to LogMAR.;The mean of central macular thickness. Timepoint: 0, ,2, 4 Months. Method of measurement: With optical coherence tomography (OCT) imaging technique (Microns).;The mean of central macular volume. Timepoint: 0, ,2, 4 Months. Method of measurement: With optical coherence tomography (OCT) imaging technique (Microns).

Secondary Outcome Measures

Name	Time	Method
Complications of the conventional laser photocoagulation. Timepoint: 2, 4 Months. Method of measurement: Fundus examination and fluorescein angiography.;Complications of the subthreshold diode micropulse laser. Timepoint: 2, 4 Months. Method of measurement: Fundus examination and fluorescein angiography.