Effect of Surgeon Volume on Outcome of Pancreaticoduodenectomy in a High Volume Hospital.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 610
- 试验地点
- 1
- 主要终点
- Postoperative mortality after pancreaticoduodenectomy within 30 days of discharge
研究概览
简要总结
The independent impact of surgeon volume on outcome of patients undergoing pancreaticoduodenectomy in a high-volume Institution was assessed. A significant reduction of pancreatic fistula rate was found in the high-volume surgeon group in comparison with low-volume surgeon group. However, no difference between groups was found in mortality, major complications, and hospital stay.
详细描述
Objectives: To define the independent impact of surgeon volume on outcome after pancreaticoduodenectomy (PD) in a single high-volume institution.
Summary Background Data: The impact of surgeon volume on PD outcome is still controversial. So far, data available are from retrospective multi-institutional reviews, considering in-hospital mortality as the only outcome variable.
Methods: Prospectively collected data on 610 patients who underwent PD from August 2001 to August 2009 were analyzed. Cut-off value to categorize high and low-volume surgeons (HVS and LVS, respectively) was 18 PD/year. Primary endpoint was operative mortality (death within 30-day post-discharge). Secondary endpoints were morbidity, pancreatic fistula (PF) and length of stay. Demographic, clinical, and surgical variables were recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who underwent pancreaticoduodenectomy between August 2001 and August 2009
排除标准
- •Other type of surgery
研究组 & 干预措施
Low volume surgeons
low volume surgeons performed less than 18 PD/year.
干预措施: Pancreaticoduodenectomy (Procedure)
High volume surgeons
high volume surgeons performed at least 18 PD/year.
干预措施: Pancreaticoduodenectomy (Procedure)
结局指标
主要结局
Postoperative mortality after pancreaticoduodenectomy within 30 days of discharge
时间窗: 30 days after discharge
次要结局
- Postoperative morbidity rate measuring the following complications: pancreatic fistula, biliary fistula, delayed gastric emptying, infectious complications, bleeding, cardiovascular complications, respiratory complications.(30 days post-discharge)
- Postoperative hospital stay. Measuring the length of hospital stay.(At day of discharge)