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Finasteride effect as a treatment for spontaneous retinal edema

Phase 1
Conditions
Central Serous Chorioretinopathy.
Separation of retinal layers
Registration Number
IRCT2013083114530N1
Lead Sponsor
Shahid Sadoughi University of Medical Science
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Eligibility criteria:patients with chronic CSCR, which was defined in this study as 1) the presence of subretinal fluid, as determined by spectraldomain OCT;2)the subretinal fluid must have been present for at least 3 months or there was a recurrence of subretinal fluid in ipsilateral eye within the past 3 months.
exclusion criteria:corticosteroid use,CNV or other ocular disease that disturb the study outcome,pregnant and nursery women

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Best corrected visual acuity. Timepoint: by the intervention initiation,15 days,1,2 and 3 months after intervention,3months after discontinuation of intervention. Method of measurement: Snellen chart.;Central macular thickness. Timepoint: by the intervention initiation,15 days,1,2 and 3 months after intervention,3months after discontinuation of intervention. Method of measurement: spectral domain OCT.;Subretinal fluid volume. Timepoint: by the intervention initiation,15 days,1,2 and 3 months after intervention,3months after discontinuation of intervention. Method of measurement: spectral domain OCT.
Secondary Outcome Measures
NameTimeMethod
Adverse effects(decreased libido,impotence,improper ejaculation,postural hypotension,dizziness). Timepoint: 15 days,1,2 and 3 months after intervention. Method of measurement: pation history taking.
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