Lingual Nerve Injury in Patients With Difficult Intubation

• Conditions: Lingual Nerve Injuries; Difficult Intubation
• Interventions: Other: Observational

• Registration Number: NCT04195152
• Lead Sponsor: Istanbul Medeniyet University

Brief Summary

The aim of this study is to investigate the incidence of lingual nerve injury and related factors in difficult intubation cases.

Demographic data of difficult intubation cases and body mass indices, thyromental and sternomental distances, mallampati classification, neck circumference, maximum mouth opening be recorded.Numbness of the tongue and metallic taste will be questioned

Detailed Description

The lingual nerve is the anterior descending branch of the posterior trunk of the mandibular division of the trigeminal nerve.

Lingual nerve injury is a recognised complication of orotracheal intubation and has been associated with forceful laryngoscopy.

Although left-sided neuropraxia has been reported, right-sided lesions are thought to be more common because the standard Macintosh laryngoscope exerts pressure on the right side of the tongue.

Lingual nerve injury following orotracheal intubation was first described in 1971 by Teichner who reported a right-sided neuropraxia which was attributed to direct pressure from the laryngoscope.

Study Timeline

• Status Verified: 2019-12
• Study Start: 2019-12-01
• Study First Submitted: 2019-12-04
• Study First Submitted QC: 2019-12-10
• Last Update Submitted: 2019-12-10
• Study First Posted: 2019-12-11
• Last Update Posted: 2019-12-11
• Primary Completion: 2020-06-30
• Study Completion: 2020-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

All adult patients undergo general anesthesia who have difficulty in intubation will be included in the study. The same number of patients without intubation difficulties will be included in the study as a control group.

Exclusion Criteria

1. Patients who are not intubated under general anesthesia
2. Patients undergoing regional anesthesia or peripheral nerve block
3. Patients with laryngeal mask placed will not be included in the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Difficult intubation group	Observational	An intubation is called difficult if a normally trained anesthesiologist needs more than 3 attempts or more than 10 min for a successful endotracheal intubation.
Non difficult intubation group	Observational	An intubation is called non difficult if a normally trained anesthesiologist needs only one attempt for a successful endotracheal intubation.

Primary Outcome Measures

Name	Time	Method
The incidence of lingual nerve injury	1 year	The frequency of lingual nerve injury in patients with difficult intubation seen in one year period will be determined.

Secondary Outcome Measures

Name	Time	Method
Rate of emergency tracheotomy	1 year
Incidence of cardiovascular complications	1 year
Percentage of patients with teeth injuries	1 year
Percentage of patients with oral mucosa injuries	1 year
Percentage of patients with temporary difficulty in swallowing	1 year
Percentage of patients with temporary difficulty in breathing	1 year
Incidence of inability to taste	1 year
Percentage of patients with metallic taste in the tongue	1 year
Incidence of numbness in the tongue	1 year

Trial Locations

Locations (1)

Istanbul MU Goztepe Training and Research Hospital; 🇹🇷 Istanbul, Turkey