CTRI/2025/08/093168尚未招募4 期
Comparative evaluation of nebulized dexamethasone with nebulized dexmedetomidine for reduction in incidence of post-operative sore throat in patients undergoing laparoscopic cholecystectomy under general anesthesia with endotracheal intubation
ABHISHEK CHATTERJEE0 个研究点目标入组 132 人开始时间: 2025年9月2日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 132
- 主要终点
- incidence and severity of postoperative sore throat
研究概览
简要总结
132 Patients fulfilling the inclusion criteria will be randomly allocated into three equal groups. Group S will receive 8mg nebulized dexamethasone. Group D will receive 50mcg nebulized dexmedetomidine and Group P will receive 5ml nebulized normal saline. The incidence and severity of postoperative sore throat along with incidence of hoarseness of voice and cough will be observed at four different time points after extubation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •ASA 1 ASA 2 Scheduled for elective laparoscopic cholecystectomy surgery.
排除标准
- •ASA 3 ASA 4 history of allergy to study drugs anticipated difficult airway uncontrolled comorbid conditions.
结局指标
主要结局
incidence and severity of postoperative sore throat
时间窗: 2 hours, 6 hours, 12 hours, 24 hours after extubation
次要结局
- incidence of hoarseness of voice, cough(2 hours, 6 hours, 12 hours, 24 hours after extubation)
研究者
ABHISHEK CHATTERJEE
TATA MAIN HOSPITAL
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