The effect of laser on eye in diabetic patients
Not Applicable
- Conditions
- Diabetic retinopathy.Diabetic retinopathy
- Registration Number
- IRCT2014030116782N1
- Lead Sponsor
- Tehran University Of Medical Sciences, Farabi Hospital, Ophthalmic Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
Presence of severe Nonproliferative diabetic retinopathy or Proliferative diabetic retinopathy in both eyes; Normal intraocular pressure; Refractive error within ±3 diopter (D).
Exclusion criteria: Any type of previous retinal treatment ( macular or peripheral laser photocoagulation, vitrectomy, intravitreal steroids and/or antiangiogenic drugs); Glaucoma or ocular hypertension; Significant media opacities that precluded fundus examination or imaging; Other retinal or optic nerve disease; Uncontrolled systemic hypertenion (BP = 180/110); Central macular thickness = 350
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Macular thickness. Timepoint: before intervention, 1, 3 and 6 months after intervention. Method of measurement: Spectral domain optical coherence tomograghy ( SD_OCT ).;Macular choroidal thickness. Timepoint: before intervention, 1, 3 and 6 months after intervention. Method of measurement: Spectral domain optical coherence tomograghy ( SD_OCT ).;Peripapillary nerve fiber layer thickness. Timepoint: before intervention, 1, 3 and 6 months after intervention. Method of measurement: Spectral domain optical coherence tomograghy ( SD_OCT ).
- Secondary Outcome Measures
Name Time Method Best Corrected Visual Acuity ( BCVA ). Timepoint: before intervention, 6 month after intervention. Method of measurement: Snellen acuity chart.;Total number of laser burns. Timepoint: after any PRP session. Method of measurement: by laser setting.