Comparative Evaluation of Post-Operative outcomes of Modified Carnoy’s Solution Versus 5-Flurouracial Used For Chemical Cauterization Following Enucleation And Peripheral Ostectomy In Patients With Odontogenickerato Cyst
概览
- 阶段
- Post Marketing Surveillance
- 状态
- 尚未招募
- 发起方
- Dr NIdhi Vijaykumar Bodiwala
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Assess the rate of Odontogenic keratocyst recurrence within a defined follow-up period.
概览
简要总结
The current study aims to compare and evaluate the post-operative outcomes with respect to recurrence rate of modified Carnoy’s solution versus 5-Flurouracial used for chemical cauterization following enucleation and peripheral ostectomy in patients with odontogenic keratocyst.
Odontogenic cysts are one of the common entities in head and neck region which is a pathological cavity having fluid, semifluid or gaseous contents and which is not created by the accumulation of pus.
It may or may not be lined by epithelium and can exist as single or multiple cavities. Cyst without cystic linings is termed as pseudo-cysts.
Odontogenic cysts are usually missed-diagnosed when symptomless unless they are infected or have an destructive nature showing adjacent bone resorption resulting in large bony cavities. Radicular cysts comprising of 48.67% are the most commonly occurring of all odontogenic cysts, followed by follicular cysts and odontogenic keratocyst.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients included in this study will be histologically proven cases of OKC with the age range of
- •70 years.
- •Patients having cystic lesion of size more than 2 cm in greatest diameter.
- •Patient having interincisal mouth opening of at least 30mm.
- •Patients who are non-smokers and non-alcoholic.
排除标准
- •Patients having cystic lesion of size less than 2 cm in diameter.
- •All patients who are contraindicated with multiple cystic lesion
- •All previously treated patient with same diagnosis of OKC.
- •Patients with immunocompromised status.
- •Pregnant and Lactating females.
结局指标
主要结局
Assess the rate of Odontogenic keratocyst recurrence within a defined follow-up period.
时间窗: 6 month ,12 month and 18 month
5-Fluorouracil (5-FU): Compare the recurrence rate with that of Modified Carnoy’s Solution.
时间窗: 6 month ,12 month and 18 month
次要结局
- NILL(NA)
研究者
NIDHI VIJAY KUMAR BODIWALA
Sharad Pawar Dental College and Hospital