ISRCTN59484478Completed未知
Assessment of Detection of Apoptosing Retinal Cells in glaucoma
St Mary's Hospital NHS Trust (UK)0 sites98 target enrollmentStarted: October 24, 2006Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 98
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •Our patient group will be identified from the glaucoma clinics at The Western Eye Hospital according to the following inclusion criteria:
- •1. For all patient groups:
- •1.1. Aged 18 years or over
- •1.2. Clear optical media in the studied eye
- •1.3. Previous experience at automated perimetry
- •1.4. No ocular or systemic disease (other than glaucoma in the test group)
- •1.5. Refractive error not higher than spherical equivalent of 6 D
- •1.6. Best corrected visual acuity equal to 6/9 or better
- •2. All subjects will have to have been shown to be able to perform reliable visual field testing using the HFA 640 instrument, central 24-2 program, to yield full thresholds (Deviation, MD-HFA and Pattern Standard Deviation, PSD-HFA), and have had good fundoscopy with assessment of their optic disc
- •3. Subjects willing and able to make the required study visits
- •4. All subjects must be able to understand the information describing the study and give informed consent
Exclusion Criteria
- •1. History of current or severe, unstable or uncontrolled cardiovascular, hepatic or renal disease (e.g., sinus bradycardia, cardiac failure) precluding safe administration of a topical beta antagonists
- •2. History of bronchial asthma or chronic obstructive airways disease precluding use of a topical beta antagonist
- •3. Women of childbearing age will be excluded from the study unless they have been surgically sterilised
- •4. Contact lens wearers will not be allowed to participate in the study
- •5. Previous ocular surgery such as retinal detachment, multiple surgical procedures including glaucoma
- •6. Co-existing disease which may affect DARC count e.g., retinal vein occlusion, age-related macular degeneration (AMD)
Investigators
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