Combining Behavioral Treatment With Agonist Maintenance
Overview
- Phase
- Phase 3
- Intervention
- methadone
- Conditions
- Cocaine-Related Disorders
- Sponsor
- Yale University
- Enrollment
- 168
- Locations
- 1
- Primary Endpoint
- Withdrawal symptoms
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this study is to evaluate whether the community reinforcement approach (CRA) plus contingency management (CM) is more effective overall than CRA only in reducing illicit opioid and cocaine use during agonist maintenance treatment and at 3 and 6 month follow-up after completion of study protocol, and to compare the efficacy of maintenance on buprenorphine to methadone when maintenance is combined with CRA only or CRA plus CM.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Arms & Interventions
1
Methadone + CM (contingency management)
Intervention: methadone
2
methadone + VC (voucher control)
Intervention: methadone
3
Buprenorphine + CM
Intervention: Buprenorphine
4
Buprenorphine + VC
Intervention: Buprenorphine
Outcomes
Primary Outcomes
Withdrawal symptoms
Opioid and cocaine use
Social and psychological functioning
Depression
Time Frame: 24 weeks
AIDS risk behavior