Pronostic Assessment of Mortality Among Locally Advanced or Metastatic Renal Cell Carcinoma Patients After First Line Treatment : Multicenter Prospective Cohort Study With Historic Medical Data

The hypothesis of this study are as follows:

• Prognostic evaluation of patients based on an integrative model provides better assessment of overall survival, and thus improves setting of care goals.
• In a routine care population, antitumour drugs may have a significant impact on overall survival through their targeted antitumor effect, but also through their toxicity profile and their impact on comorbidities.
• The optimization of patient support (supportive care, drug tolerance monitoring) can have an impact on the prognosis.