Effects of Whey Protein Combined With Carbohydrates in the ERAS Protocol on the Recovery of Thyroid Cancer Patients After Lateral Neck Dissection: A Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 127
- 试验地点
- 1
- 主要终点
- hemoglobin
研究概览
简要总结
Exploring the effects of whey protein combined with carbohydrates in an Enhanced Recovery After Surgery (ERAS) protocol on the postoperative recovery of thyroid cancer patients undergoing lateral neck dissection, aiming to provide more precise research and guidance for the perioperative accelerated recovery plan in such patients. The goal is to accelerate postoperative recovery and reduce postoperative complications for thyroid cancer patients undergoing neck dissection.
详细描述
Perioperative dietary management was differentiated between the two groups:
Experimental Group:
6 hours before surgery, patients orally consumed 250 ml of a full-nutrition liquid (220 ml homogenized diet, 50 g; containing 31.4 g carbohydrates, 8 g protein, and 215 kcal).
2 hours before surgery, patients orally consumed 200 ml of a clear liquid (50 g enzymatically hydrolyzed rice powder + 0.5 g low-sodium salt; containing 47.7 g carbohydrates, 6.5 g whey protein, and 193 kcal).
After surgery, once there were no symptoms such as dizziness or vomiting, patients could start consuming clear liquids (containing 47.7 g carbohydrates, 6.5 g protein, and 221 kcal) orally every 30 minutes, 4 times on the day of surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18 years or older;
- •Differentiated thyroid cancer with lateral lymph node dissection;
- •Written informed consent provided by the participant.
排除标准
- •History of chronic liver or kidney disease, ischemic heart disease, or diabetes;
- •Previous neck surgery or history of iodine-131 radiation;
- •Allergy to soy or whey protein;
- •Intraoperative chylous leak;
- •Other special types of thyroid cancer.
结局指标
主要结局
hemoglobin
时间窗: 3 day
Record the difference in indicators before and after surgery
serum albumin
时间窗: 3 day
the difference in indicators before and after surgery.
weight
时间窗: 1week
Record the difference in indicators before and after surgery
Postoperative Complication
时间窗: 1 month
Record the occurrence of related surgical complications in the experimental group and the control group.
次要结局
未报告次要终点