The Ultrasonographic Changes of Intercostal Muscles and Diaphragm in Mechanically Ventilated Preterm Neonates
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The impact of mechanical ventilation on diaphragm and intercostal muscles using ultrasound
研究概览
简要总结
Invasive mechanical ventilation induces ventilator induced diaphragmatic dysfunction particularly when used for long time and Intercostal muscles as well contribute to the important work of respiratory movement by expanding the thorax , and determining the thickness of them would be a useful parameter in evaluating respiratory muscle activity.
This study will add the impact of mechanical ventilation on the diaphragm and intercostal muscles in preterm infants using ultrasound.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 5 Minutes 至 28 Days（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Preterm infants from 28-36 weeks gestation
- •In need for invasive mechanical ventilation according to work of breathing, oxygen saturation and blood gases .
排除标准
- •Significant congenital anomalies including cardiac, abdominal or respiratory.
- •Congenital anomalies involving the diaphragm. 3) Phrenic nerve paralysis. 4) Congenital muscular dystrophies. 5) Major upper or lower airway anomalies. 6) Storage diseases.
结局指标
主要结局
The impact of mechanical ventilation on diaphragm and intercostal muscles using ultrasound
时间窗: 6 months
Using Ultrasound to measure Intercostal Muscles thickness and diaphragmatic thickness and excursion for assessing the impact of the mechanical ventilation on muscle power predicting weaning from ventilation.
次要结局
未报告次要终点
研究者
Noha Saied Ibrahim
Resident at Pediatrics hospital ainshams university
Ain Shams University