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Clinical Trials/NCT05495763
NCT05495763
Unknown
Not Applicable

The Ultrasonographic Changes of Intercostal Muscles and Diaphragm in Mechanically Ventilated Preterm Neonates

Noha Saied Ibrahim1 site in 1 country30 target enrollmentAugust 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Mechanical Ventilation Complication
Sponsor
Noha Saied Ibrahim
Enrollment
30
Locations
1
Primary Endpoint
The impact of mechanical ventilation on diaphragm and intercostal muscles using ultrasound
Last Updated
3 years ago

Overview

Brief Summary

Invasive mechanical ventilation induces ventilator induced diaphragmatic dysfunction particularly when used for long time and Intercostal muscles as well contribute to the important work of respiratory movement by expanding the thorax , and determining the thickness of them would be a useful parameter in evaluating respiratory muscle activity.

This study will add the impact of mechanical ventilation on the diaphragm and intercostal muscles in preterm infants using ultrasound.

Registry
clinicaltrials.gov
Start Date
August 2022
End Date
January 2023
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Noha Saied Ibrahim
Responsible Party
Sponsor Investigator
Principal Investigator

Noha Saied Ibrahim

Resident at Pediatrics hospital ainshams university

Ain Shams University

Eligibility Criteria

Inclusion Criteria

  • Preterm infants from 28-36 weeks gestation
  • In need for invasive mechanical ventilation according to work of breathing, oxygen saturation and blood gases .

Exclusion Criteria

  • Significant congenital anomalies including cardiac, abdominal or respiratory.
  • Congenital anomalies involving the diaphragm. 3) Phrenic nerve paralysis. 4) Congenital muscular dystrophies. 5) Major upper or lower airway anomalies. 6) Storage diseases.

Outcomes

Primary Outcomes

The impact of mechanical ventilation on diaphragm and intercostal muscles using ultrasound

Time Frame: 6 months

Using Ultrasound to measure Intercostal Muscles thickness and diaphragmatic thickness and excursion for assessing the impact of the mechanical ventilation on muscle power predicting weaning from ventilation.

Study Sites (1)

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