Effectiveness of timolol mouthwash to prevention chemotherapy-induced mucositis
Phase 2
Recruiting
- Conditions
- Chemotherapy-induced mucositis.Encounter for antineoplastic chemotherapyZ51.11
- Registration Number
- IRCT20190810044500N9
- Lead Sponsor
- Yazd University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
All patients over 18 years of age undergo chemotherapy
Adequate literacy to fill out a consent form, understand the study, use the drug, report pain and possible side effects
Exclusion Criteria
Intolerance to medication, misuse of mouthwash
People with a history of bradycardia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical presentation. Timepoint: Before starting chemotherapy, after starting chemotherapy every week and finally one week after the end of mouthwash consumption (8 visits in total). Method of measurement: Oral examination.;The severity of mucositis. Timepoint: Before starting chemotherapy, after starting chemotherapy every week and finally one week after the end of mouthwash consumption (8 visits in total). Method of measurement: Oral examination and checklists for WHO in 5 grades.;The severity of the pain. Timepoint: Before starting chemotherapy, after starting chemotherapy every week and finally one week after the end of mouthwash consumption (8 visits in total). Method of measurement: Oral examination based on the VAS index.
- Secondary Outcome Measures
Name Time Method Quality of life. Timepoint: End of the study. Method of measurement: According to the questionnaire EORTC QLQ-C30 (version 3).;Complications observed. Timepoint: End of the study. Method of measurement: Based on the doctor's observation and the person's statements.