Allium Sativum Extract as an Irrigant in Pulpectomy of Primary Molars: 12 Month In-vivo Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 91
- 主要终点
- oral examination
研究概览
简要总结
Garlic extract as herbal compound has potent antibacterial properties and can be used safely as an irrigant for pulpectomy procedure of primary molars root canals with high clinical and radiographic outcomes
详细描述
Aim: This study indented to assess the clinical and radiographic assessment of garlic extract as an intracanal irrigant for pulpectomy of primary molars.
Methodology: 91 child with 100 teeth submitted into this study were equally categorized into the test group (group 1) which irrigated with garlic extract and control group (group 2) that received sodium hypochlorite (NaOCl). Then, each group has been subjected to further specification according to the tooth preoperative clinical and radiographic features into has been into 2 subgroups. Clinical and radiographic success rates were checked at 3, 6 and 12 months. Fisher's exact test for binary variable was used for data analysis with p-value ≤ 0.05.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 4 Years 至 6 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Class I or II according to American Society of Anesthesiologists (ASA)
- •Irreversible pulpititis recognised through; (1) profuse bleeding from root canal orifices after complete debridement of coronal pulp tissue and cannot be dominated by moist cotton pellet. (2) History of lingered thermal pain spontaneous nocturnal pain
- •Necrotic pulp tissues which may be asymptomatic or manifested with dull ache pain
- •Pathological tooth mobility
- •Percussion sensitivity
- •Swelling close to involved tooth accompanied with or without fistula Radiographic characteristics of the root and supporting structures
- •Normal radiographic findings
- •Interruption of lamina dura
- •Furcation radiolucency
排除标准
- •Specifications of exclusion
- •Uncooperativeness of child and/or parents or caregivers behavior
- •Unrestorable tooth
- •Presence of internal root resorption
- •Presence of calcific metamorphosis inside root canals
- •Presence of root resorption exceeding one third of its length
研究组 & 干预措施
Garlic extracts root canal irrigation group
Experimental group treated with garlic extract
A 100 gram of garlic cloves has been cleaned, peeled and dried. Ethanol of 70% concentration was added for 60 seconds. The cloves were placed in a laminar airflow chamber for evaporation of residual ethanol. Using a sterile mortar and pestle, cloves were homogenized aseptically and filtered through a double layer paper. The fully concentrated extracted was diluted to the concentration of 25% with distilled water
干预措施: Garlic extract (Other)
Sodium hypochlorite root canal irrigation group
Control group which treated conventionally using .5 ml of 5.25% NaOCl (COLTENE®ENDO, Switzerland)
干预措施: NaOCl (COLTENE®) (Other)
结局指标
主要结局
oral examination
时间窗: 12 months
Pain assessment using Visual Analog Score for pain
radiographic success or failure
时间窗: 12 months
Radiographic assessment using periapical radiograph and score (0) applied for absence of radiolucency and score (1) for presence of radiolucency
次要结局
- Types of failures(12 months)
研究者
Ahmad Elheeny
Lecturer of pediatric dentistry
Minia University