How Astigmatism Influences Corneal Biomechanics and Intraocular Pressure

Completed

• Conditions: Corneal Astigmatism; Intraocular Pressure; Cataract Senile

• Registration Number: NCT03162471
• Lead Sponsor: Medical University of Lodz

Brief Summary

The aim of the study was to identify whether preoperative corneal astigmatism can influence corneal biomechanics and the assessment of intraocular pressure (IOP) following micro-incision phacoemulsification.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-05-01
• Primary Completion: 2016-12-01
• Study Completion: 2016-12-01
• Status Verified: 2017-05
• Study First Submitted: 2017-05-17
• Study First Submitted QC: 2017-05-19
• Last Update Submitted: 2017-05-19
• Study First Posted: 2017-05-22
• Last Update Posted: 2017-05-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

• diagnosis and qualification for cataract surgery, corneal astigmatism of equal to or less than 2.25 Dcyl

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Exclusion Criteria

• corneal astigmatism higher than 2.25 Dcyl, history of any other corneal disease (infection, trauma, ulceration, autoimmune inflammation, Fuchs Dystrophy, keratoconus, corneal scars, preoperative insufficiency of corneal endothelium), glaucoma and chronic use of non-glaucoma eye drops, blepharitis, dry eye, use of contact lenses diabetes or a history of corneal refractive surgery

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
change of corneal compensated IOP (IOPcc)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.

Secondary Outcome Measures

Name	Time	Method
change of corneal resistance factor (CRF)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.
change of Goldman-correlated IOP (IOPg)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.
change of corneal hysteresis (CH)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.
change of waveform score (WS)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.