Correlation of Fibrinogen to Albumin Ratio and C-reactive Protein to Albumin Ratio With Disease Activity in Juvenile Idiopathic Arthritis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 主要终点
- The fibrinogen to albumin ratio
研究概览
简要总结
The fibrinogen to albumin ratio (FAR) and C-reactive protein to albumin ratio (CAR) have emerged as useful biomarkers to predict systemic inflammation. The aim here is to investigate the relation between FAR/CAR and Juvenile arthritis disease activity score (JASDAS27) in Juvenile idiopathic arthritis (JIA)
详细描述
The JADAS27 includes a selected count of the following joints: cervical spine, elbows, wrists, metacarpophalangeal joints (from first to third), proximal interphalangeal joints, hips, knees and ankles.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- — 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All juvenile idiopathic arthritis fulfilling the criteria of International League of Associations for Rheumatology (ILAR) and age and sex matched healthy subjects
排除标准
- •Other systemic inflammatory or autoimmune disorders.
- •History of corticosteroid medication in the last 6 months.
- •Liver diseases.
- •Malignancy.
结局指标
主要结局
The fibrinogen to albumin ratio
时间窗: 3 months
measurement of serum fibrinogen and albumin
Correlation of fibrinogen to albumin and CRP to albumin ratios on one side with disease activity on the other side
时间窗: 3 MONTHS
correlation of these ratios with JADAS27
The CRP to albumin ratio
时间窗: 3 MONTHS
measurement of serum CRP and albumin
次要结局
未报告次要终点
研究者
Maha Sayed Ibrahim Abdelrahman
principal investigator
Assiut University