Biomarker analysis in septic intensive care patients
- Conditions
- blood poisoningSepsis10002252
- Registration Number
- NL-OMON36605
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 2067
Age: 18 years and older
Presence of an arterial line;Sepsis group: Patients admitted to the intensive care with sepsis, or patients developing sepsis during their stay on the intensive care.;SIRS patients: Critically ill patients who score positive on at least two SIRS criteria who do not suffer from sepsis and have an expected ICU stay of more than 24 hours.;Healthy volunteers: All healthy individuals without any recent febrile or infectious illness (within 2 weeks). Individuals capable of giving written informed consent.
No informed consent;Patients receiving more than 24 hours of antibiotic treatment for a suspected infection prior to ICU admission.;Sepsis group: Previous participation in this study.;SIRS group: Previous participation in this study.;Healthy volunteers: Previous participation in this study.
A major illness in the past 3 months or any significant chronic medical illness that the investigator would deem unfavorable for enrolment, including inflammatory diseases.
A recent febrile illness (within 2 weeks).
Recent use of anti-inflammatory medication (within 2 weeks).
Subject using tobacco and/or illicit drug products.
Current use of hormone therapy or current pregnancy.
Limited accessibility of a vein in the left or right arm.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>90-day mortality</p><br>
- Secondary Outcome Measures
Name Time Method