A Controlled Clinical Study On The Therapeutic Efficacy Of Katibasti With Agnitaila In Gridhrasi (Sciatica)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Improvement in the clinical signs and symptoms of Gridhrasi
研究概览
简要总结
Low Back Pain with sciatica is one of the most significant health problems in current-day practice. It also contributes to social life as well as economic crises in the form of deterioration in work productivity. Low back pain is the prime factor for disability & ranks 6th for the overall burden on the world population. The lifetime incidence of sciatica is reported to be between 10% to 40% and an annual incidence of 1% to 5%. The majority of incidence occurs in the 4th – 5th decade of the working population.Gridhrasi is one among the Shoola pradhana vataja nanatmaja vyadhi & it can be correlated to the disease Sciatica in contemporary science which can manifest as either Vataja type or Vatakaphaja type. The common symptom seen as Kramatah shoola from Sphik, Kati, Prista, Uru, Janu, Jangha & Pada associated with Stambha, Toda, Muhur spandana & Sakthikshepa nigraha in Vataja type whereas in Kaphanubandhi type it is associated with Tandra, Gourava & Aruchi .Sciatica is a debilitating condition that occurs most often due to herniation of a disc or an overgrowth of bone that puts pressure on part of the nerve which leads to low back pain that begins with the lumbosacral region and radiates along with the posterio-lateral aspects of the thigh to leg with difficulty in walking & paresthesia that travels along the path of the sciatica nerve. The management of sciatica includes analgesics, anti-inflammatory drugs, steroid injections & physiotherapy . Prolonged usage of these may lead to many adverse effects.Ayurveda classics explain the treatment for Vatavyadhi in detail in which Snehana, Swedana & Mridu shodhan are the prime line of treatment for vitiated Vatadosha. The Chikitsa sutra mentioned for Gridhrasi as Bastikarma, Siravyadha, Agnikarma & Virechana karma are considered as Vishesha chikitsa .The proper execution of these treatment principles will help in relieving the symptoms of the Gridhrasi.Katibasti is a form of Snehayukta sweda and also Samshamaneeya bahirparimarjan chikitsa. The combination of Snehana & Swedana in Katibasti works together in relieving the Shoola, Stambha, etc. so that one can achieve symptomatic relief by increasing in functional ability of the affected region .Agnitaila is a proprietary medicine and consists of ingredients like Tila, Punnaga, Nirgundi, Lavanga, Maricha, Lashuna & Sarshapa being Ushnaveerya dravya are having the Vatahara, Shoolahara, Stambhahara and also Kaphahara in action.Nirgundi taila consists of ingredients like Nirgundi, Langali & Tila being Ushnaveerya dravya having the Vatahara, Shoolahara, Stambhahara and also Kaphahara in action.The Snehayukta sweda in the form of Katibasti may give significant relief in the treatment of Vatavyadhi. Hence an attempt is made to see the therapeutic efficacy of Katibasti with Agnitaila has been taken for the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •1 Patients fulfilling the diagnostic criteria of Gridhrasi (Sciatica) 2 Age group 30-50 years 3 Patients with positive physical signs / special test of Sciatica 4 Patients who are voluntarily willing to sign consent form.
排除标准
- •1 Congenital deformities of the lumbar spine 2 Malignant conditions of the lumbar spine 3 Infective, inflammatory diseases of lumbar spine 4 Traumatic conditions of the lumbar spine like Compressive fractures, Quada equina compression 5 AVN head of femur 6 Pregnancy 7 Any other systemic illness like uncontrolled DM, HTN etc which interfering the treatment 8 Post-surgical conditions of lumbar spine.
结局指标
主要结局
Improvement in the clinical signs and symptoms of Gridhrasi
时间窗: Duration of study 10 days | Follow up 20th day | Total study period 20 days | 1st assessment (before treatment) | 2nd assessment 10th day(After Treatment) | Follow up 20th day(without assessment)
(Reduction in pain radiating from lower back along the pathway of sciatica nerve till the foot)
时间窗: Duration of study 10 days | Follow up 20th day | Total study period 20 days | 1st assessment (before treatment) | 2nd assessment 10th day(After Treatment) | Follow up 20th day(without assessment)
次要结局
- •Improvement in the functionality is assessed through Oswestry Disability Index (Questionnaire’s method)(1st assessment (before treatment))
研究者
Dr Allappa Kumbar
Shri Dharmasthala Manjunatheshwara Institute of Ayurveda and Hospital Bengaluru
