EFFECT OF MAKARADHWAJA ON DIABETESE (MADHUMEHA)

Phase 2

Completed

• Conditions: Type 2 diabetes mellitus without complications,

• Registration Number: CTRI/2013/12/004200
• Lead Sponsor: Institute for Post Graduate Teaching and Research in Ayurveda

Brief Summary

In this study a comparative clinical trial of *Shadguna Makaradhwaja* will be studied on patients of Type II D.M. (*Madhumeha*) with *Guduchi Ghanna* and *Madhu* as adjuvants.Selected patients will be randomly divided into two groups,Group A:  14.63 mg *Makardhwaja* prepared by *Swarna Varkha*  + 235.37 mg *Guduchi* *Ghana* tablet – bd, orally with *Madhu*.Group B: 14.63 mg *Makardhwaja* prepared by *talastha swarna bhasma* + 235.37 mg *Guduchi Ghana* tablet – bd, orally with *Madhu*. for a duration of 4 weeks.Patients will be reviewed after 7 days for a period of 4 weeks.Blood sugar level will be monitered  every week.patients will be redirected to regular OPD treatment after the stipulated time of research work.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01-11
• Study Completion: 2014-12-31
• Last Update Posted: 2019-11-18

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

•Patients having classical symptomatology of Madhumeha (Type II D.M.) •Symptoms of Diabetes (Polyuria, Polydypsia, Polyphagia and Weight loss.) •Fasting plasma glucose ≥ 126 mg/dl and Post prandial glucose level ≥ 200 mg/dl.

Exclusion Criteria

• •Patients of Diabetes Mellitus receiving Insulin.
• •Patients having chronic complications of Diabetes Mellitus 1.Microvascular: Retinopathy, Neuropathy, & Nephropathy.
• 2.Macrovascular: Coronary artery disease, Peripheral vascular disease & Cerebro-vascular disease.
• 3.Other chronic debilitating diseases like STD,TB,Leprosy .

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
•Improvement in the signs and symptoms of the disease as per Ayurvedic texts.	4 weeks
•Blood sugar level will be monitered with glucometer every week.	4 weeks
•Investigations conducted before and after the treatment.	4 weeks

Secondary Outcome Measures

Name	Time	Method
Improvement will be assessed on the basis of	relief found in cardinal symptoms of

Trial Locations

Locations (1)

Institute for Post Graduate Teaching and Research in Ayurveda; 🇮🇳 Jamnagar, GUJARAT, India

Institute for Post Graduate Teaching and Research in Ayurveda

🇮🇳Jamnagar, GUJARAT, India

VAIBHAV CHARDE

Principal investigator

9723153948

vaibhavayudoc@gmail.com