MedPath

Imaging the brain of children with obesity.

Conditions
Obesity (according to the international criteria of Cole et al (2000)
BMI in adults between 30-35 kg/m2)
Registration Number
NL-OMON27404
Lead Sponsor
Prof.dr.H.A.Delemarre-van de WaalProf. of PediatricsHead Dep. PediaticsLUMC University Hospital LeidenP.O.Box 96002300RC LeidenThe Netherlands0031715262824
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Other
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

Cases and controls:

1. Male (n=10) and female (n=10);

Exclusion Criteria

Cases:

1. Overweight caused by a medical problem (determined by our standard protocol);

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Structural measurements of neural structures involved in eating behavior (amygdala, nucleus accumbens, hippocampus, insula) in obese and non-obese adolescents;<br /><br>2. Neuronal responses in a resting state condition in obese and non-obese adolescents;<br /><br>3. Neuronal responses to food stimuli (eg prefrontal cortex) in obese and non obese adolescents.
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath