Prospective Randomized Clinical Trial Evaluating the Impact of Vinegar on High Density Lipoprotein

HealthPartners Institute1 site in 1 country114 target enrollmentJune 2008

ConditionsCholesterol, HDL

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Cholesterol, HDL
Sponsor: HealthPartners Institute
Enrollment: 114
Locations: 1
Primary Endpoint: Change in HDL-Cholesterol level
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This is a double-blinded randomized placebo controlled prospective clinical trial evaluating the impact of apple cider vinegar on serum HDL. 112 participants will be randomized to consume either 2 tablespoons of vinegar daily or a placebo containing a 2% balsamic vinegar solution in water. Baseline, two month and 4 month blood samples will be obtained for fasting lipids. The primary endpoint is met if HDL levels increase in the treatment arm versus baseline after 2 month intervention.

Registry

clinicaltrials.gov

Start Date

June 2008

End Date

July 2010

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

HealthPartners Institute

Eligibility Criteria

Inclusion Criteria

•Those older than 18 years of age
•Park Nicollet Health Services patient

Exclusion Criteria

•Because of a potential positive effect of vinegar on improving diabetes mellitus8 and the subsequent change in medication regime for diabetes diabetic patients will be excluded from this study. If this study finds that vinegar does increase HDL levels, a subsequent study of diabetic patients will be conducted.
•History of allergy to apple cider vinegar
•Those with a terminal illness
•Diagnosis of Inflammatory bowel disease
•Those with Immunosuppression diseases
•Patients on dialysis
•Severe psychiatric illness who are unable to consent or reliably participate
•No evidence of end stage renal disease
•Those who use alcohol greater than or equal to 2 drinks per day
•Those who take in \>3 tsp vinegar/day supplement