The effect of selenium on nephropathy complications of diabetic patients

Phase 2

• Conditions: diabetic nephropathy.; non-insulin-dependent diabetes mellitus with renal complications; E11.2

• Registration Number: IRCT2015060622562N1
• Lead Sponsor: Vice chancellor for research, Kashan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Diabetic nephropathy with a proteinuria level of >0.3 g/24 hours
With or without circulating levels of serum creatinine

Exclusion Criteria

The consumption of selenium supplements within 3 months before beginning of the study
Patients with uncontrolled diabetes
Pregnant women
Liver diseases
Inflammatory diseases
Bacteriuria
Haematuria
Urinary tract infection
History of hospital admission within 3 months

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum insulin. Timepoint: Before and three months after intervention. Method of measurement: In serum sample will assessed by ELISA kit. mU/ml.;Inflammatory factor hs-CRP. Timepoint: Before and three months after intervention. Method of measurement: In serum sample will assessed by ELISA kit. ng/ml.;Insulin resistance. Timepoint: Before and three months after intervention. Method of measurement: Calculation using HOMA formula.