Effects of Probiotic supplementation associated with Tube Feeding on Infections and Blood Sugar control of patients in intensive care unit

Not Applicable

Recruiting

• Conditions: Enteral Nutrition; E02.642.500

• Registration Number: RBR-2kqnj2t
• Lead Sponsor: niversidade Federal do Paraná

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-08-24
• Last Update Posted: 18 September 2023
• Study Completion: 2024-08-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

ndividuals of both sexes; aged 18 years or older; who are hospitalized in an intensive care unit; who have indication of enteral nutrition via nasogastric, nasoenteral or gastrostomy tube will be included

Exclusion Criteria

Individuals who do not present hemodynamic conditions to receive enteral diet, patients with lesions in the gastrointestinal tract that make it impossible to receive enteral diet, patients who are in palliative treatment, who undergo immunosuppressive treatment, who have heart valve prosthesis or valve graft, who have a history of endocarditis, history of rheumatic fever, recent postoperative period of intestinal anastomosis, biliary tract and pancreas surgery, intestinal ischemia, patients with hematological and rheumatological diseases, as recommended by the 2018 Brazilian guideline for nutritional therapy in critically ill patients (BRASPEN, 2018)

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected to find a reduction in the number of infections occurring within the ICU for patients who use probiotics associated with enteral nutrition compared to the control group, observed by the percentage difference in the number of infections that will occur in the research participants

Secondary Outcome Measures

Name	Time	Method
It is expected to find a reduction in capillary glycemia in patients who use probiotics associated with enteral nutrition compared to the control group, observed by the percentage difference in insulin use to patients. ;It is expected to find a reduction in the length of stay in the ICU for patients receiving probiotics compared to the control group, observed by the difference in the number of days they are hospitalized in the intensive care unit;It is expected to find a reduction in the duration of mechanical ventilation in patients receiving probiotics compared to the control group, observed by the difference in the number of days they are on mechanical ventilation