Prevalence and Consequences of Hyperlactemia Following Pancreatic Surgery

Completed

• Conditions: Pancreatic Cancer; Pancreatic Cyst; Chronic Pancreatitis

• Registration Number: NCT06589102
• Lead Sponsor: Karolinska University Hospital

Brief Summary

The goal of this observational study is to investigate the role of lactate elevation.

The main aims are:

* Determine the frequency of lactate elevation following pancreatic surgery and its relationship to postoperative complications

* Investigate what patient and surgical related factors that are associated with postoperative lactate elevation This is a retrospective study based on existing medical data and will not affect the medical care of the studied patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-12-28
• Primary Completion: 2023-01-30
• Study Completion: 2023-03-30
• Study First Submitted: 2023-05-09
• Status Verified: 2024-09
• Study First Submitted QC: 2024-09-05
• Last Update Submitted: 2024-09-05
• Study First Posted: 2024-09-10
• Last Update Posted: 2024-09-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 491

Inclusion Criteria

• Patients undergoing pancreatic surgery 2016-2018

Exclusion Criteria

• Patients unable to undergo scheduled surgery
• Missing data in the postoperative period

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Length of hospital stay	All patients are followed until they leave the hospital, but a maximum of six months	hospital stay following surgery

Secondary Outcome Measures

Name	Time	Method
General postoperative complications	All patients are followed until they leave the hospital, but a maximum of six months	Defined as Clavien-Dindo grade III-V
ICU care	All patients are followed until they leave the hospital, but a maximum of six months	Organ failure requiring ICU care
Surgery specific complications	90 days	Pancreatic fistula, bile leakage, delayed gastric emptying

Trial Locations

Locations (1)

Karolinska University Hospital; 🇸🇪 Huddinge, Stockholm, Sweden