The Use of Stromal Vascular Fraction for Knee Arthrosis
- Conditions
- Knee Arthrosis
- Registration Number
- NCT06171204
- Lead Sponsor
- University Hospital, Ghent
- Brief Summary
A trial to investigate the safety and efficacy of SVF for the treatment of knee arthrosis.
Patients will undergo a single liposuction to obtain the SVF. The SVF will then be isolated and frozen in our laboratory. The SVF will then be injected up to 2 times into the fat pad of the patient's knee.
- Detailed Description
Stromal Vascular Fraction (SVF) from adipose tissue is increasingly being used in the clinic for a variety of conditions (skin disorders, joint pain, etc.). SVF is a collective term for cells that can be obtained from liposuction fat. These cells can be separated from the fat by mechanical processing of the liposuction fat combined with an additional centrifugation.
Despite the fact that enough SVF can be isolated after such a liposuction for multiple treatments (\>3), our research group has found a way to safely freeze SVF without significant loss of SVF cells. In this way, a patient would only have to undergo one liposuction and associated anesthesia to be able to obtain multiple SVF treatments.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 10
- Legal capacity
- Osteochondral lesions
- Inflammatory complaints
- (Peri)tendinitis or tendinopathies and ligamentous injuries
- Impingement complaints
- Arthrofibrosis
- Anterior knee pain
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Evaluation of the safety of SVF injections after cryo preservation 1 year The patient will complete the KOOS questionnaire (Knee Injury and Osteoarthritis Outcome Score) on several timepoints.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UZ GENT
🇧🇪Gent, Oost-Vlaanderen, Belgium