Treatment of Macular Edema Caused by Leber's Miliary Aneurysms Using Intravitreal Aflibercept and Peripheral Laser Photocoagulation
Not Applicable
- Conditions
- Macular Edema Caused by Leber's Miliary Aneurysms
- Interventions
- Other: Panretinal photocoagulation
- Registration Number
- NCT03908723
- Lead Sponsor
- Alexandria University
- Brief Summary
This study evaluates the effectiveness of intravitreal Aflibercept (IVA) injection therapy, combined with peripheral laser photocoagulation, in the treatment of macular edema caused by Leber's miliary aneurysm. We believe that our study makes a significant contribution to the literature because to our knowledge, it is the first to report cases, in which IVA injection therapy was used to treat this condition.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 6
Inclusion Criteria
- FA revealed many aneurysms with leakage in the temporal mid-peripheral retina and near the macula. Optical coherence tomography (OCT) showed moderate to marked cystoid macular edema and subretinal fluid. There were no abnormal findings in the cornea, anterior chamber, or lens. No particular lesions were found in the opposite eye of each subject. Based on these findings, the patients were diagnosed with Leber's miliary aneurysm.
Exclusion Criteria
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description all patients in the study Panretinal photocoagulation -
- Primary Outcome Measures
Name Time Method Visual acuity improvement 6 months after 3 consequative injections
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Alexandria university
🇪🇬Alexandria, Egypt