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Bioequivalency Study of Torsemide Tablets Under Fed Conditions

Not Applicable
Completed
Conditions
Edema
Registration Number
NCT00602615
Lead Sponsor
Roxane Laboratories
Brief Summary

The objective of this study was the bioequivalence of a Roxane Laboratories' Torsemide Tablets, 20 mg, to Demadex® Tablets, 20 mg (Roche) under fed conditions using a single-dose, 2-treatment, 2-period, crossover design.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
28
Inclusion Criteria
  • No clinically significant abnormal findings on the physical examination, medical history, or clinical laboratory results during screening.
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Exclusion Criteria
  • Positive test for HIV, Hepatitis B, or Hepatitis C.
  • Treatment with known enzyme altering drugs.
  • History of allergic or adverse response to Torsemide or any comparable or similar product.
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Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
BioequivalenceBaseline, Two period, Seven day washout
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Bio-Kinetic Clinical Applications, Inc.

🇺🇸

Springfield, Missouri, United States

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