To assess the glucose and metabolic hormones response in obese children, following 3 rice based meals containing 3 types of resistant starch, in view of reducing obesity in childre
Not Applicable
Recruiting
- Conditions
- Obesity in children
- Registration Number
- SLCTR/2020/007
- Lead Sponsor
- Sri Lanka College Of Paediatricians
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
•Both male and female children
•Age between 10-12 years
•BMI centile over 95% [BMI between +2SD and +3SD in WHO chart]
•Obese children with normal glucose metabolism (HbA1C <5.7%) and without other comorbidities such as hypertension (blood pressure less than 95th centile for height, sex and age), hyperlipidemia
Children with normal ultra sound liver and stage I fatty liver (mild fatty liver)
Exclusion Criteria
* Children with chronic diseases such as, hypertension, hyperlipidemia, pre-diabetes/diabetes mellites, fatty liver grade >2
* BMI > 3SD in WHO chart
* Children with renal, liver, lung, and neurological disorders
* Children on corticosteroids
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess and compare the plasma glucose response using fasting and postprandial blood sugars tests [60, 120, 180 minutes after each test meals ]<br>To assess and compare the post prandial plasma insulin, leptin and ghrelin after ingestion of the following test meals using ELISA method [120 minutes after each test meal]<br>To assess and compare plasma leptin, PYY and GLP 1 response using ELISA method [ 180 minutes after each test meal]<br>Satiety and hunger using an in-house visual analog scale analog scale to measure the subjective response [15, 60,120 and 180 min [after each test meal?]]<br>
- Secondary Outcome Measures
Name Time Method one []<br>