NCT05679648尚未招募不适用
Evaluation of Hepatic Steatosis and Fibrosis in Rheumatoid Arthritis Patients: a Cross-sectional Case-control Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 主要终点
- degree of hepatic fibrosis
研究概览
简要总结
studying the prevalence of hepatic steatosis and fibrosis in a large scale of patients with RA and healthy controls
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •RA according to the American College of Rheumatology (ACR)/EULAR 2010 criteria (Aletaha et al., 2010)
- •Age≥18 years
排除标准
- •History of hepatitis B and C virus infection.
- •Receiving hepatotoxic drugs other than RA-specific drugs.
- •Alcohol abuse (i30 g/day in men and ⩾20 g/day in women).
- •Diagnosis of Wilson's disease, α1-antitrypsin deficiency or hemochromatosis.
- •Autoimmune liver disease.
- •Pregnancy.
结局指标
主要结局
degree of hepatic fibrosis
时间窗: 1 day during examination
degree of hepatic fibrosis by FIB-4 and APRI tests
degree of hepatic steatosis
时间窗: 1 day during examination
degree of hepatic steatosis by ultrasonography and Hepatic Steatosis Index.
次要结局
未报告次要终点
研究者
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