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Clinical Trials/NCT03231072
NCT03231072CompletedNot Applicable

Effects of the Pleural Effusion Drainage in Mechanically Ventilated Patients Monitored by Electrical Impedance Tomography and End-Expiratory Lung Volume

Czech Technical University in Prague2 sites in 1 country19 target enrollmentStarted: January 31, 2017Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
19
Locations
2
Primary Endpoint
Change of the thorax electrical impedance following pleural effusion drainage in mechanically ventilated patients

Study Overview

Brief Summary

Evacuation of pleural effusion (PE) represents a disputable therapy in mechanically ventilated patients. Patients on mechanical ventilation indicated by the physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured in order to describe impact of PE evacuation on aeration and ventilation of the lungs.

Detailed Description

Critically ill patients treated in intensive care units have a disorder of distribution and volume of body fluids due to principal illness and some therapeutic interventions. One of its manifestations is pleural effusion (PE) formation.

Patients on mechanical ventilation indicated by treating physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured. The purpose of the study is to better understand impact of PE evacuation on aeration and ventilation of the lungs.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Diagnostic
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • mechanical ventilation, presence of pleural effusion, decision of the treating physician to drain it

Exclusion Criteria

  • impossibility to apply EIT belt or to find suitable save point for drainage when the EIT belt is attached
  • standard EIT exclusion criteria according to the device manufacturer

Outcomes

Primary Outcomes

Change of the thorax electrical impedance following pleural effusion drainage in mechanically ventilated patients

Time Frame: 4 hours

Comparison of EIT results with end-expiratory lung volume measurement during drainage of pleural effusion

Secondary Outcomes

  • Change of the distribution of ventilation following pleural effusion drainage in mechanically ventilated patients(4 hours)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (2)

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