Visual Outcomes of Topography Guided Photorefractive Keratectomy (PRK) for Treatment of Patients With Irregular Cornea
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Assiut University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Visual Acuity
Study Overview
Brief Summary
Irregular astigmatism is one of the most serious and frequent complications of corneal refractive surgery and one of the worst sequelae of other forms of corneal surgery . It is also considered as one of common, serious complications of corneal injuries .
Spectacle correction is usually not useful in the correction of corneal irregular astigmatism. Contact lenses represent a good alternative, but their adaptation and stability are limited by the irregular corneal surface and patient discomfort.
In recent years, advancements in laser technology have offered better tools for dealing with irregular astigmatism with finding new surgical methods to improve corneal regularity for the correction of irregular astigmatism.
Topography-linked excimer laser is a potentially effective technique in the treatment of irregular astigmatism after keratoplasty . In fact, customized ablation was shown to be an effective means of treatment of irregular astigmatism due to different etiologies Such as corneal Injuries , scar , or postoperative.
Some of the theoretical advantages of topography-driven photorefractive keratectomy (PRK) are a better astigmatic correction, the possibility of correcting irregular astigmatism, and a smaller ablation volume compared with standard treatments, resulting in better visual performance.
Aim of the work To evaluate the efficacy, safety, and predictability of topography-guided photorefractive keratectomy (PRK) to improve refractive status of patient with irregular Cornea.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with irregular corneal astigmatism caused by:
- •Non - Central Corneal Scars.
- •Previous corneal surgery.
- •With No other abnormalities in the eye.
- •Patient is willing to enter the study and sign a consent.
Exclusion Criteria
- •Patients with central corneal scars.
- •Patients with central haze interfering with visual acuity.
- •Patients with ectasia at corneal graft margins.
- •Patients with irregular astigmatism caused by corneal ectasia or keratoconus.
- •Patients had refractive surgery with ablations leaving a residual corneal thickness less than 250 μm.
Arms & Interventions
Corneal Topography
we will do Corneal Topography for every patient before doing photorefractive keratectomy (PRK) and also after it , to measure the change in the quality of vision and measure the change in the quality of vision
Intervention: photorefractive keratectomy (PRK) (Procedure)
Outcomes
Primary Outcomes
Visual Acuity
Time Frame: follow up after 1 day, 1 week, 1 month and 3 months
The measure of the Visual Acuity and Best Corrected Visual acuity Using the Snellen Chart which give use an idea about visual acuity in Metric scale (e.g. 6\\6 , 6\\12)
Secondary Outcomes
- Refractive State(follow up after 1 day, 1 week, 1 month and 3 months)
Investigators
Ahmed Abdelsamee Mohammed
Dr
Assiut University
