Visual Outcomes of Topography Guided Photorefractive Keratectomy (PRK) for Treatment of Patients With Irregular Cornea
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Visual Acuity
研究概览
简要总结
Irregular astigmatism is one of the most serious and frequent complications of corneal refractive surgery and one of the worst sequelae of other forms of corneal surgery . It is also considered as one of common, serious complications of corneal injuries .
Spectacle correction is usually not useful in the correction of corneal irregular astigmatism. Contact lenses represent a good alternative, but their adaptation and stability are limited by the irregular corneal surface and patient discomfort.
In recent years, advancements in laser technology have offered better tools for dealing with irregular astigmatism with finding new surgical methods to improve corneal regularity for the correction of irregular astigmatism.
Topography-linked excimer laser is a potentially effective technique in the treatment of irregular astigmatism after keratoplasty . In fact, customized ablation was shown to be an effective means of treatment of irregular astigmatism due to different etiologies Such as corneal Injuries , scar , or postoperative.
Some of the theoretical advantages of topography-driven photorefractive keratectomy (PRK) are a better astigmatic correction, the possibility of correcting irregular astigmatism, and a smaller ablation volume compared with standard treatments, resulting in better visual performance.
Aim of the work To evaluate the efficacy, safety, and predictability of topography-guided photorefractive keratectomy (PRK) to improve refractive status of patient with irregular Cornea.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with irregular corneal astigmatism caused by:
- •Non - Central Corneal Scars.
- •Previous corneal surgery.
- •With No other abnormalities in the eye.
- •Patient is willing to enter the study and sign a consent.
排除标准
- •Patients with central corneal scars.
- •Patients with central haze interfering with visual acuity.
- •Patients with ectasia at corneal graft margins.
- •Patients with irregular astigmatism caused by corneal ectasia or keratoconus.
- •Patients had refractive surgery with ablations leaving a residual corneal thickness less than 250 μm.
结局指标
主要结局
Visual Acuity
时间窗: follow up after 1 day, 1 week, 1 month and 3 months
The measure of the Visual Acuity and Best Corrected Visual acuity Using the Snellen Chart which give use an idea about visual acuity in Metric scale (e.g. 6\\6 , 6\\12)
次要结局
- Refractive State(follow up after 1 day, 1 week, 1 month and 3 months)
研究者
Ahmed Abdelsamee Mohammed
Dr
Assiut University
