CTRI/2025/07/091712尚未招募不适用
Effect of mixture versus sequential injections of lignocaine and bupivacaine on block characteristics for supraclavicular brachial plexus nerve block in patients undergoing upper limb surgery. A randomised clinical trial.
Dr Dakshatha Cr1 个研究点 分布在 1 个国家目标入组 152 人开始时间: 2025年9月15日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 152
- 试验地点
- 1
- 主要终点
- To assess the duration of sensory block
研究概览
简要总结
This study is a randomised, double blind, parallel group, trail comparing the effect of mixture versus sequential injections of 2% lignocaine with adrenaline and 0.5% bupivacaine for supraclavicular brachial plexus nerve block in 152 patients undergoing upper limb surgery. The primary outcome measures will be the duration of sensory block. The secondary outcomes will be onset of sensory and motor block, the duration of motor block, the duration of analgesia, the percentage of patients having block in all four nerve areas by 15 min.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Under ASA grade 1 and 2, weighing 60kg and above, willing to give informed written consent, planned for unilateral upper limb surgery.
排除标准
- •Coagulation or bleeding disorders, Local site infection ,Any nerve injury or neuropraxia or paralysis, History of allergy or anaphylaxis to bupivacaine or lignocaine, Pregnant and lactating females.
结局指标
主要结局
To assess the duration of sensory block
时间窗: 24 hours
次要结局
- To assess the onset of sensory and motor block. To assess the duration of motor block. To assess the duration of analgesia. To determine the percentage of patients having block in all four nerve areas by 15 min.(24 hours)
研究者
Dr Dakshatha Cr
Bangalore medical college and research institute
研究点 (1)
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