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Effect of Diet and Exercise Program for Chronic Hepatitis C with Insulin Resistance - Impact on liver function and virological response to Pegylated Interferon alpha-2b/Ribavirin

Not Applicable
Conditions
Chronic hepatitis C
Registration Number
JPRN-UMIN000003044
Lead Sponsor
Saga Medical School
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up continuing
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

(1)pregnancy, its possibility or lactation (2)hypersensitivity to IFN, pegylated IFN or ribavirin (3)uncontrollable cardiac disease (4)hemoglobinopathy (5)creatinine clearance less than 50 mL/min (6)severe mental illnesses such as depression or past history (7)decompensated liver disease (8)autoimmune hepatitis (9)taking medication for DM or poor control of blood glucose levels

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
(1) the degree of improvement in liver function (2) the virological responce rate
Secondary Outcome Measures
NameTimeMethod
(1) the degree of improvement in HOMA-IR (2) the change of body weight and waist circumference
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