Comparison the effectiveness of microneedling with SRGF versus conventional microneedling in periorbital skin rejuvenation in middle-aged wome

Phase 2

Recruiting

Conditions: Skin Rejuvenation.
Atrophic disorder of skin, unspecified
L90.9

Registration Number: IRCT20140911019125N4

Lead Sponsor: Skin & Stem Cell Research Center, Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 50

Inclusion Criteria

Female gender
Presence of aging signs of periorbital with grade 3-5
Patients aged between 30-50 years
Patients desire to microneedling and blood sampling

Exclusion Criteria

Menopause patients
Patients that received systemic retinoids treatments (in recent 6 months) or local retinoids treatments (in recent 2 weeks)
History of hemorrhagic disorders or recent receiving anti-coagulant treatments
Any factor that inhibit low invasive techniques
Patients with autoimmune diseases.
Women in pregnant or lactation period
Doing skin procedures and racer-facing lasers

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Skin Elasticity. Timepoint: Before intervention and 2 months after intervention. Method of measurement: Specific Equipment.;Skin Moisture. Timepoint: Before intervention and 2 month after intervention. Method of measurement: Specific Equipment.;Skin Pigmentation distribution. Timepoint: Before intervention and 2 months after intervention. Method of measurement: Specific Equipment.;Sebum Activity. Timepoint: Before intervention and 2 months after intervention. Method of measurement: Specific Equipment.;Skin oil. Timepoint: Before intervention and 2 months after intervention. Method of measurement: Specific Equipment.;Skin Wrinkle. Timepoint: Before intervention and 2 months after intervention. Method of measurement: Examination.

Secondary Outcome Measures