TO know the lowest volume of a drug combination to block the nerves of the hand

Phase 4

Completed

Conditions: Male patients age between 20 and 40 years with below elbow fractures

Brief Summary: **When using LA toprovide surgical anesthesia , we need to provide**

1. Dense blockade

2. The duration of block should be such that it coversthe entire duration of surgery and also provides adequate pain relief duringthe immediate post â€“operative period.

Our previous experience with supraclavicularbrachial plexus block, has shown that lignocaine- bupivacaine combination cansatisfy these two requirements.

The previous study by Transetal, (3) have reported that 23 ml of the drugcombination is the MEV required to produce block in 50 % of patients and MEV 95is 42 ml.

We are however able to produce block in all patientsby using 20 ml of the drug combination. So we decided to conduct this study to estimate the minimum effective volume to produce effective block using Masseys up and down method and hence determine the ED 95

Recruitment & Eligibility

Inclusion Criteria

ASA 1 and 2 Patients posted for bony surgery below elbow.

Exclusion Criteria

1. Patient refusal for the block 2) History of bleeding disorders 3) Local infection at the site of block 4) Pre-existing neurological deficit 5) Respiratory compromise.
1. Known allergy to local anaesthetic drug.
1. Patients in whom the supraclavicular sono-anatomy is not clear.

Primary Outcome Measures

Name	Time	Method
volume of mixture of 2 % lignocaine with adrenaline and bupivacaine that can produce a successful motor and sensory block at 30 minutes.	Assessment of sensory and motor block every 10 minutes upto 30 minutes

Secondary Outcome Measures

Name	Time	Method
Duration of analgesia	Every 2 hrs till 6 hours

Locations (1): Mahatma Gandhi Medical College and Research Institute
🇮🇳
Pondicherry, PONDICHERRY, India
Mahatma Gandhi Medical College and Research Institute
🇮🇳Pondicherry, PONDICHERRY, India
Dr Gobinath J
Principal investigator
8098023218
gobigopi@gmail.com