MedPath

STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners

Not Applicable
Not yet recruiting
Conditions
Frontotemporal Dementia
Caregiver Burden
Primary Progressive Aphasia(PPA)
Corticobasal Syndrome
Interventions
Behavioral: STELLA-FTD Control
Behavioral: STELLA-FTD Test
Registration Number
NCT06613204
Lead Sponsor
Oregon Health and Science University
Brief Summary

The purpose of this nationwide study is to test STELLA-FTD (Support via Telehealth: Living and Learning with Advancing Alzheimer's Disease)-FTD, an intervention to specifically address the needs of family Care Partners of persons with frontotemporal degeneration (FTD). STELLA-FTD is a multicomponent video-conference based intervention designed to facilitate effective use of community and peer resources to foster effective management of behavioral and psychological symptoms of dementia. The study is recruiting families from across the US.

Detailed Description

The study will enroll a total sample of up to 640 participants: 320 family care partners and their 320 care Recipients with FTD. For our study "family Care Partner" includes any person who is considered "family" to the person with FTD, such as direct relations, fictive kin, close friends and neighbors. "Care Recipient" is defined as an individual with an FTD diagnosis noted by the AFTD: bv-FTD, PPA, progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), or ALS with FTD. Care Recipients with FTD will not participate in intervention but will be consented (and thus enrolled) because data will collected about them. The study will test to see if our program helps Care Partners.

The STELLA-FTD intervention is delivered over 8 sessions within 10 consecutive weeks in 1-hour "live" video-based group sessions led by two guides. There will be two intervention groups, the control group and the test group. There will be up to 8 care Partners per group, which allows for the development of mutual trust and commitment.

Care Partners will be randomized to either the test or control group using an electronic randomization process and will be blinded to their group designation. Both groups will receive information and support (via videoconferencing). The test group will receive a different program than the control group. Care Partners will fill out 6 long surveys while in the study, and a weekly brief survey.

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
640
Inclusion Criteria

Family Care Partner

  • Adult caring for family member with FTD.
  • Provides 4 or more hours of care/week. Does not have to reside with.
  • Identifies at least 2 moderately upsetting behaviors in the person with FTD.
  • Speaks and understands English to be able to participate in intervention.
  • Owns a telephone (smartphone, cell phone or landline).
  • Has email and mailing address to receive computer, study materials and surveys.
  • Provides informed consent to participate in the research.
  • Lives in the US

Inclusion Criteria: Person with FTD

  • Diagnosis of FTD
  • Family member of a Care Partner (this can be a relative, spouse, or close kin that is considered family).
  • Lives in US
Exclusion Criteria

Person with FTD

  • No Frontotemporal Degeneration diagnosis.
  • Unable to leave Care Partner during STELLA-FTD sessions.
  • Enrolled in hospice.

Exclusion Criteria: Family Care Partner

  • Unable to find activity for Care Recipient during STELLA-FTD sessions to allow Care Partner to work privately with Guide and other Care Partners.
  • Hearing and/or vision problems severe enough to prevent participation.
  • Refuses to be video-recorded during STELLA-FTD sessions.
  • Unwilling or unable to adequately follow study instructions and participate in study procedures.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Control GroupSTELLA-FTD ControlControl group, receives information and support in a group setting (n=160 Care Partners)
Test GroupSTELLA-FTD TestTest group, receives information and support in a group setting, but program is different from control (N=160 Care Partners)
Primary Outcome Measures
NameTimeMethod
Revised Memory and Behavior Problems Checklist, Frequency, Original Scale1 month pre-intervention; 1 week pre-intervention, 4 weeks after intervention start; 8 week post intervention; 2 and 6 months post intervention

Efficacy will be assessed by measuring pre/post changes on the RMBPC. The RMBPC is a 24-item caregiver report measure, 5-point Likert scale with higher scores on frequency indicate more upsetting behaviors Frequency range is 0 (never occurred) to 4 (daily or more often). Frequency score range is 0 to 96

Revised Memory and Behavior Problems Checklist, Reactivity, Original Scale1 month pre-intervention; 1 week pre-intervention, 4 weeks after intervention start; 8 week post intervention; 2 and 6 months post intervention

Efficacy will be assessed by measuring pre/post changes on the RMBPC. The RMBPC is a 24-item caregiver report measure, 5-point Likert scale with higher scores on reactivity indicate more Care Partner burden. Frequency range is 0 (no burden) to 4 (high burden). Frequency score range is 0 to 96

Secondary Outcome Measures
NameTimeMethod
Self-efficacy for symptom management and support service use1 month pre-intervention; 1 week pre-intervention, 8 week post intervention; 2 and 6 months post intervention

10-item scale to measure self-efficacy. Assesses caregiver certainty that they will use services and support programing. 1= not at all certain, to 10=very certain. Scores range from 10 to 100, with 100 being high certainty.

Neuropsychiatric Inventory-Caregiver Self-efficacy Scale1 month pre-intervention; 1 week pre-intervention, 8 week post intervention; 2 and 6 months post intervention

Measures frequency of behaviors related to frontotemporal dementia and Care Partner confidence in managing behaviors. Frequency is rated on a scale of 1 (occasionally) to 4 (very frequently), severity is rated from 1 (mild) to 3 (severe), and caregiver distress is rated from 0 (no distress) to 5 (extreme or very severe). Total scores are calculated by multiplication of the frequency and severity for each symptom and the addition of all item scores, with a range of 0-144. The distress score total is calculated by the sum of all the individual domain scores, with a range of between 0 and 60. If a behavioral symptom is noted, the care partner is asked to about how confident they are in addressing it, Responses range from 4 (not at all confident), 3 (fairly confident), 2 (confident), and 1 (very confident).

Preparedness for Caregiving Scale1 month pre-intervention; 1 week pre-intervention, 8 week post intervention; 2 and 6 months post intervention

10-item measure that assesses how prepared care partners feel to care for their family member with dementia. Ranges from 0 (not at all prepared) to 40 (very well prepared).

Personalized Target Behavior Survey1 week pre-intervention, 8 week post intervention

On STELLA-FTD Website, measures frequency and reactivity of up to 3 personalized behaviors identified by Care Partners. Care partners rate how often the 5-point Likert scale with higher scores on frequency indicate more upsetting behaviors Frequency range is 0 (never occurred) to 4 (daily or more often). Frequency score range is 0 to 4 for each Target behavior. Higher scores indicate higher frequency and burden.

Service and Support use survey1 month pre-intervention; 1 week pre-intervention, 8 week post intervention; 2 and 6 months post intervention

10-item survey that queries participants about service use. Score is not on a scale.

Support via Telehealth: Living and Learning with Advancing Frontotemporal Dementia Experience Survey1 week post intervention

18-item- survey on satisfaction, privacy, ease of use. Scores range from 1 (strongly disagree) to 5 (strongly agree). Total score ranged 18-90, higher scores are better

Orbit SurveyWeekly, starts at Week 1, ends after week 36.

Weekly survey of burden, service use, medication use. Score is not on a scale.

Revised Memory and Behavior Problem Checklist Frontotemporal Degeneration Supplement, Frequency1 month pre-intervention; 1 week pre-intervention, 4 weeks after intervention start; 8 week post intervention; 2 and 6 months post intervention

Measures frequency of upsetting frontotemporal behaviors. 9 items, scores range from 0 (no behaviors) to 36 (all behaviors)

Revised Memory and Behavior Problem Checklist Frontotemporal Degeneration Supplement, Reactivity1 month pre-intervention; 1 week pre-intervention, 4 weeks after intervention start; 8 week post intervention; 2 and 6 months post intervention

Measures caregivers reactions to upsetting frontotemporal behaviors. 9 items, scores range from 0 (no reactivity) to 36 (high reactivity)

Clinical Dementia Rating Scale plus Frontotemporal Lobar DegenerationOne time assessment at enrollment

This is an 8-item survey that assesses disease severity, with 0=no impairment to 3=severe impairment. Range is 0-24 (Sum of boxes)

Ten Item Personality InventoryOnce, at Week 1 of intervention

10 items that assess personality type. Respondents note how they agree with each. personality type, from

1=Disagree strongly 2 = Disagree moderately 3 = Disagree a little 4 = Neither agree nor disagree 5 = Agree a little 6 = Agree moderately 7 = Agree strongly

Score is not on a scale.

Contact SurveyWeek 13, 20, and 36

Nine questions query caregivers about if they contacted other caregivers in the study, and, if so, how often. Score is not on a scale

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