Acupuncture for patients with chronic spontaneous urticaria: A randomized, sham-controlled pilot trial
- Conditions
- Chronic Urticaria
- Registration Number
- ITMCTR2100005452
- Lead Sponsor
- Chengdu University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- Not specified
Eligible participants were diagnosed by three specialists in dermatology according to EAACI/GA2LEN/EDF/WAO guidelines for CSU and participants met the following inclusion criteria were included: 1) the sudden appearance of wheals, angioedema, or both; 2) the occurrence of spontaneous wheals, angioedema, or both for = 6 weeks; 3) suffering from urticaria at least twice a week on average during the previous 6 weeks; 4) aged between 18 to 70 years; 5) antihistamines were not used within 2 weeks before entering the study; 6) steroids hormone and immunosuppressive drugs were not used within 1 month; 7) agreed to participate in this study and signed written informed consent.
Participants meeting any of the following criteria were excluded: 1) urticaria was inducible by physical factors (e.g., cold urticaria, delayed pressure urticaria, solar urticaria, heat urticaria, vibratory angioedema); 2) suffering from neurological diseases, mental disorders, immunodeficiency, bleeding disorders; 3) having any serious disease of the heart, liver, kidney, or other organs; 4) having severe cognitive impairment; 5) pregnant or lactating; 6) involved in other clinical studies at the same time.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rticaria Activity Score;
- Secondary Outcome Measures
Name Time Method Dermatology Life Quality Index;Hamilton Depression Scale;Visual Analogue Scale (VAS) score of itching intensity;Hamilton Anxiety Scale;