Nutritional Status Among naïve HIV Infected Patients and HIV Infected Patients Receiving Highly Active Antiretroviral Therapy

Completed

• Conditions: HIV Infections

• Registration Number: NCT01899157
• Lead Sponsor: Thai Red Cross AIDS Research Centre

Brief Summary

A prospective cross-sectional study evaluates nutritional status and its relationship to the related factors in Thai HIV-infected patients who attending in out patient clinic.

Detailed Description

A prospective cross-sectional study evaluates nutritional status and its relationship to the related factors in Thai HIV-infected patients who attending in out patient clinic at The Thai Red Cross AIDS Research Centre, Bamrasnaradura Infectious Disease Institute, Surat Thani hospital, Khonkaen hospital, Sanpathong hospital and the Queen Savang Vadhana Hospital at Sri Racha .

General Objective: To determine nutritional status among Thai People Living with HIV (PLHIV).

Specific Objective:

1. To assess nutritional problems including undernutrition, overnutrition and others such as lipodystrophy, dyslipidemia, hyperglycemia, cardiovascular disease, etc. among naïve HIV-infected patients and HIV-infected patients undergoing HARRT by using ABCDEF approach: Anthropometric, Biochemical, Clinical, Dietary, Exercise and Family assessment.

2. To describe the relationship between the nutritional status and HIV disease staging and other related factors among naïve HIV-infected patients and HIV-infected patients undergoing HARRT.

3. To describe the prevalence of CVD and its relationship to cardiac risk factors

4. To validate the community screening tool developed by the Thai Nutrition Taskforce in HIV (TNT-HIV) by assessing the correlation of this tool and nutritional status.

Study Timeline

• Study Start: 2009-08
• Primary Completion: 2010-12
• Study Completion: 2011-12
• Study First Submitted: 2013-06-06
• Status Verified: 2013-07
• Study First Submitted QC: 2013-07-10
• Last Update Submitted: 2013-07-10
• Study First Posted: 2013-07-15
• Last Update Posted: 2013-07-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 580

Inclusion Criteria

• HIV positive
• 18 years of age or older
• Receiving ongoing care as part of the anonymous clinic, TRCARC, the antiretroviral therapy clinics at Bamrasnaradura Infectious Disease Institute, Surat Thani hospital, Khonkaen hospital, Sanpathong hospital and the Queen Savang Vadhana Hospital at Sri Racha.
• Either naïve HIV-infected patients and HIV-infected patients undergoing HARRT

Exclusion Criteria

• HIV negative
• Patient who had active AIDS-related disorders within three months before participate the study
• Patients who are pregnant

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Nutritional status and Nutritional situation	1 year	Nutritional status and Nutritional situation in Naïve HIV infected patients and HIV-infected patients undergoing HAART. It will be collected by using ABCDEF approch: Anthropometric, Biochemistry, Clinical, Dietary, Exercise and Family assesment.

Secondary Outcome Measures

Name	Time	Method
The prevalence of metabolic syndrome	1 year	The prevalence of metabolic syndrome in Naïve HIV infected patients and HIV-infected patients undergoing HARRT using American Heart Association (AHA) and National Heart Lung and Blood Institute (NHLBI) criteria

Trial Locations

Locations (1)

Thai Red Cross AIDS Research Centre; 🇹🇭 Bangkok, Pathumwan, Thailand