Role of Dopamine Transporter in Glucose Loading of Healthy Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Specific binding ratio of dopamine transporter availabilitiy measured from PET scans
研究概览
简要总结
Healthy subjects will be enrolled in this study. Each subject will be scanned twice with F18-FP-CIT PET which is commercially available. F18-FP-CIT reflects dopamine transporter availability of striatum. Before each PET scan, subject will be injected either glucose or normal saline. Therefore, PET scan will reflect the changes of dopamine transporter availability after the injection of glucose.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy subjects
排除标准
- •known neurologic disorder
- •known drug addiction
- •known endocrine disorder
研究组 & 干预措施
Healthy subjects
All subjects will be injected twice for each visit (normal saline or glucose)
干预措施: Glucose injection/Normal saline injection (Other)
结局指标
主要结局
Specific binding ratio of dopamine transporter availabilitiy measured from PET scans
时间窗: less than 1 month
Specific binding ratio of dopamine transporter availabilitiy measured from PET scans
次要结局
未报告次要终点
研究者
Kyoungjune Pak
Clinical Assistant Professor
Pusan National University Hospital