Impact of an Artificial Intelligence Platform on Inappropriate Medication Use in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 178
- 试验地点
- 9
- 主要终点
- Number of patients with decrease in STOPP criteria number between initial prescription and exist prescription.
研究概览
简要总结
Polypharmacy in the older adults is common and promotes the risk of drug interactions. The hypothesis evoked is that a virtual platform with artificial intelligence applied to the health, and in particular to the good use of the drug, could bring aids to the doctors them of the prescription of drugs. The main objective of this study is to evaluate the impact of geriatric use of the Synapse platform on the frequency of inappropriate medication prescriptions (STOPP criteria) in discharge orders for patients 65 years of age or older hospitalized in geriatric department.
详细描述
The French 2018-2022 National Health Strategy plan aims to reduce the proportion of potentially harmful medication use. One particular challenge is the phenomenon of polypharmacy and inappropriate medication use in elderly, which is associated to an increased risk of drug-drug interactions. Several scales and tools have been proposed to identify inappropriate drugs prescription in older adults. Among them, the STOPP / START criteria (Screening Tool of Older Persons' Prescriptions / Screening Tool to Alert to Right Treatment) are internationally recognized.
The Synapse platform offers a panel of functions that may help physicians to prescribe medications. For instance, the prescriber can interact with the Synapse platform by asking any type of question about a drug (dosage, contraindication, interaction ...) before prescription. It also allows them to take a picture of prescription. The software detects in less than 10 seconds criteria for inappropriate medication prescriptions and potential drug-drug interactions.
More precisely, the Synapse platform provides information on a particular drug or prescription analysis regarding:
- Indications, contraindications, dosage and adverse effects of drugs.
- STOPP criteria.
- START criteria.
- Associations at risk for drug-drug interactions.
Multiple new health technologies are emerging, but few of them have demonstrated their scientific and medical added value using an evidence-based medicine approach.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inclusion criteria:
- •Male or female age aged more than 65 years
- •Hospitalization in geriatric department at Bordeaux University Hospital or Libourne Hospital
- •Initial drug prescription with at least 2 active pharmaceutical ingredients
- •Affiliation to French social security
- •Written informed consent signed by participant and investigator
排除标准
- •Adults protected by law
- •Subject included in a clinical trial with an experimental treatment
- •Subject during exclusion period relative to another trial
研究组 & 干预措施
Assistance device
With prescription assistance device:
During the other 3 months, investigators will have the Synapse platform on different media (mobile phones, tablets, laptops and landline).
干预措施: Synapse platform (Device)
No device
During 3 months, investigators will not have the Synapse platform and will make their prescriptions with the usual tools which they have: Modules of help in the DxCare® software of the CHU, public database of the drugs, dictionary Vidal®, …
结局指标
主要结局
Number of patients with decrease in STOPP criteria number between initial prescription and exist prescription.
时间窗: Month 6
Proportion of patients with decrease in STOPP criteria number between initial prescription and exist prescription.
次要结局
- Number of patients with decrease if active pharmaceutical ingredients(Month 6)
- Number of STOPP criteria(Month 6)
- Number of START criteria(Month 6)
- number of patients with decrease in contraindicated drug-drug interaction(Month 6)
- Number of patients with increase in START criteria number between initial prescription and exist prescription.(Month 6)
- Number of connections per week on Synapse platform by geriatricians(Month 6)