Long-term Follow up of the Cases Who Underwent Conservative Surgery for Placenta Previa Accreta: a Prospective Case Series Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Menstrual pattern
研究概览
简要总结
Conservative management of placenta accreta spectrum can preserve future fertility but should only be done in hospitals with enough experience as it carries a high risk of maternal complications.
Follow up after conservative management is crucial to detect complications early.
详细描述
Placenta accreta is defined histopathologically as abnormal trophoblast invasion of part or all of the placenta into the myometrium of the uterine wall.1 Depending on the depth of villous tissue invasiveness, placenta accreta was subdivided by pathologists into "creta", "increta", and "percreta", in which the villi adhere superficially to the myometrium without interposing decidua, penetrate deeply into the uterine myometrium, and perforate through the entire uterine wall and may invade the surrounding pelvic organs, respectively.
The term placenta accreta spectrum (PAS) will be used in this manuscript to include both the abnormally adherent and the invasive forms of accreta placentation. Severe and sometimes life-threatening hemorrhage, which often requires blood transfusion, increases maternal morbidity and mortality.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women with one or more previous cesarean deliveries
- •Women diagnosed with placenta previa accreta and underwent Conservative stepwise surgical approach for management.
排除标准
- •women who refused to participate in the study.
- •Associated other medical conditions as pregnancy-induced hypertension, heart diseases, and rheumatological diseases apart from iron deficiency anemia.
- •Presence of uterine anomalies
结局指标
主要结局
Menstrual pattern
时间窗: 3-6 months
menstrual irregularities by history regarding Regular and normal volume or Regular and scanty or presence of Intermenstrual bleeding
Easiness of hysteroscopy introduction
时间窗: 3-6 months
accessibility of hysteroscopic examination
cesarean scar niche
时间窗: 3-6 months
presence of a pouch, that forms on the wall of your uterus.
Adequacy of uterine cavity
时间窗: 3-6 months
visualization of the uterus will be assessed using office hysteroscopy
intrauterine adhesions
时间窗: 3-6 months
visualization of the intrauterine adhesions will be assessed using office hysteroscopy
次要结局
未报告次要终点
研究者
Mahmoud Mohamed Ghaleb
Professor
Ain Shams Maternity Hospital