Impact of Mass Zinc Fortification Programs on Plasma Zinc Concentration
- Conditions
- Zinc Deficiency
- Registration Number
- NCT00944723
- Lead Sponsor
- University of California, Davis
- Brief Summary
The purpose of the study is to evaluate the use of plasma zinc concentration for assessing the impact of mass zinc fortification programs.
- Detailed Description
The objectives of the present study are to determine whether plasma zinc concentration changes in response to additional zinc consumption, as provided by zinc-fortified cereal-based complementary foods fed to adult men (fortified at a level consistent with currently proposed levels). The following specific steps will be completed:
1. Zinc-fortified breads prepared from zinc-fortified wheat flour will be developed with assistance from experts in food technology.
2. A four-week feeding trial will be implemented to assess the change in plasma zinc concentration among young adult men who receive: a) bread fortified with a moderate amount of zinc and a liquid vitamin preparation between meals; b) bread fortified with a large amount zinc and a liquid vitamin preparation between meals; c) non-zinc-fortified bread and a liquid vitamin preparation between meals \[negative control group\]; and d) non-zinc-fortified bread and a zinc-containing liquid vitamin preparation between meals \[positive control group\].
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 132
- apparently healthy males
- Hemoglobin <80 g/L
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Plasma zinc concentration 1 month
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Helen Keller International
🇸🇳Dakar, Senegal
Helen Keller International🇸🇳Dakar, Senegal