Investigating the effect of methylphenidate on increasing the level of consciousness in patients with hypoxic ischemic encephalopathy
- Conditions
- Hypoxic ischemic encephalopathy.Hypoxic ischemic encephalopathy [HIE]P91.6
- Registration Number
- IRCT20220924056025N1
- Lead Sponsor
- Qazvin Medical Sciences Research Deputy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 48
Patients hospitalized in the intensive care unit with the diagnosis of HIE hypoxic ischemic encephalopathy,
Aged between 18 and 65 years
Both sexes (male and female)
With some degree of reduced level of consciousness.
Patients with a history of epilepsy
Patients with high blood pressure that is newly discovered and not treated or controlled
Patients with Cardiac ischemia and arrhythmia that are newly discovered and not treated or controlled,
Patients with deafness
Patients with rapid changes in vital signs and unstable hemodynamics
Patients with multiple organ failure
Patients with hyperthyroidism
pregnancy
Drug addiction
Secondary surgery
Reluctance to attend the investigation based on the opinion of the patient's legal guardian
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Average level of consciousness based on 4 Score criteria. Timepoint: Every three days for a month. Method of measurement: Criterion 4 Score in ICU.
- Secondary Outcome Measures
Name Time Method Average biological indicators of systole and diastole blood pressure. Timepoint: Every three days for a maximum of one month. Method of measurement: Recording of ICU patient monitoring every three days for a maximum of one month.;Average biological index of arterial oxygen saturation percentage. Timepoint: Every three days for a maximum of one month. Method of measurement: Recording of ICU patient monitoring every three days for a maximum of one month.;Average biological index of heart rate. Timepoint: Every three days for a maximum of one month. Method of measurement: Recording of ICU patient monitoring every three days for a maximum of one month.