Electrophysiological Study of Interindividual Differences in Speech-understanding Among Cochlear Implant Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hearing Loss
- Sponsor
- Centre Hospitalier Universitaire de Nice
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Quantify the interactions between electrical stimulation channels based vocal performance of implanted subjects, for different subjective levels of electrical stimulation.
- Last Updated
- 13 years ago
Overview
Brief Summary
Differences in speech-understanding and the quality of the subjective perception among cochlear implant patients (Digisonic SP) depends on numerous factors. The electrical field distribution (interaction between electrodes) could also explain the disparity of the performances? The objective of our study was to quantify the influence of the electrical field interactions between the channels of stimulation according to the vocal performances of the implanted subjects, for various subjective levels of electric stimulation.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Subject of French language
- •Subject with a moderate bilateral sensorineural hearing loss, severe to profound
- •Sensorineural hearing loss post-lingual (after onset of language acquisition)
- •Subject paired with the implant Neurelec (Appendix 1) for more than 9 months
- •Subject has received an appropriate setting under usual clinical follow-up
- •Elderly 18 to 75 years
- •Subject giving consent
Exclusion Criteria
- •Sensorineural hearing loss pre-lingual
- •Deafness following a meningitis, or neurodegenerative diseases
- •Illiteracy
- •Pregnant women
- •Subject blind
- •Subject enjoying a measure of legal protection
- •Subject incapable of giving consent
- •Subject vulnerable
Outcomes
Primary Outcomes
Quantify the interactions between electrical stimulation channels based vocal performance of implanted subjects, for different subjective levels of electrical stimulation.
Time Frame: At the inclusion - Day 0
The vocal performance will be noted in percentage of voice recognition in the silence and in the noise. And the electric interaction between the channels of stimulations will be estimated by the measure of the refractory period of the circuits of the hearing system with the PEAEP after stimulations of electrodes of intermediate situation in the cochlée (electrodes 11, 12 and 13)
Secondary Outcomes
- Comparative study of PEAEP (Auditory Evoked Potentials Early electric) in vocal performance(At the inclusion - Day 0)